In cell culture studies, Epithalon has been shown to reactivate telomerase expression in human somatic cells, extending replicative capacity by 10+ additional cell divisions [1]
However, these effects are often short-lived and may be offset by the potential risk of introducing antimicrobial resistance determinants (532, 554)
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In contrast, a small fraction of lymphoma and leukemia cell lines successfully grow in these gels [28, 30], suggesting the presence of TIC or TIC-like cells even in established lymphoma/leukemia cell lines cultured in vitro